Page preview of Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: a randomised, double-blind, placebo-controlled trial

Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: a randomised, double-blind, placebo-controlled trial

Massimo Filippi, Marco Rovaris, Matilde Inglese, Frederik Barkhof, Nicola De Stefano, Steve Smith, Giancarlo Comi
November 2005
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Summary

Researchers investigated interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: a randomised, double-blind, placebo-controlled trial to clarify factors contributing to multiple sclerosis. Systematic scientific analysis examined biological and clinical data relevant to MS. Key results identified previously unrecognized mechanisms underlying MS. Understanding these mechanisms suggests new therapeutic intervention approaches. These findings have direct clinical relevance for MS patient management and outcomes. The work advances understanding of MS biology and supports development of improved therapies.